Abcam, ab117074, Anti-GPCR150 antibody

Size: 50µg
Rabbit Polyclonal GPCR150 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human GPR160 conjugated to Keyhole Limpet Haemocyanin.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human GPR160 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.Q9UJ42

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4Preservative: 0.1% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--80°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
GPCR150 also known as G-protein coupled receptor 150 is a member of the GPCR family which plays an important role in signal transduction across cellular membranes. This receptor has an approximate mass of around 40 kDa. GPCR150 is expressed mainly in the central nervous system and other tissues which signifies its broad functional relevance. As with many GPCRs the receptor transduces external signals via interaction with G proteins upon ligand binding leading to various intracellular responses.
Biological function summary
GPCR150 is involved in the modulation of signal transduction processes impacting neural communication and potentially influencing neurological functions. It may not operate alone; rather it likely functions as part of a signaling complex involving other such receptors and proteins which facilitates its role in modulating neurotransmitter signals. This involvement hints at its importance in maintaining neural network activities and related physiological responses.
Pathways
Multiple processes involve GPCR150 where it acts through the neuroactive ligand-receptor interaction pathway a well-known pathway for neuronal signaling. It associates with other proteins like G-proteins and possibly chemokine receptors which collectively contribute to the transmission and modulation of signals critical for normal brain function. The pathways and associated proteins reinforce the receptor's role in supporting key neurological activities and physiological processes.
GPCR150 has associations with conditions such as anxiety and depression. These mental health issues underline the significance of proper signaling by GPCR150 in mood regulation and emotional response. The receptor's influence on these disorders may also involve interaction with other proteins like serotonin receptors which are key players in neurotransmitter pathways affecting mood and mental states. Understanding GPCR150's role may offer potential targets for therapeutic intervention in related disorders.