Abcam, ab229571, Anti-RPS26 antibody - N-terminal

Size: 100µL
Rabbit Polyclonal RPS26 antibody. N-terminal. Suitable for WB, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human 40S ribosomal protein S26.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human 40S ribosomal protein S26. The exact immunogen used to generate this antibody is proprietary information.P62854

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.025% Proclin 300Constituents: PBS, 20% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
RPS26 also known as ribosomal protein S26 is a part of the ribosomal machinery involved in protein synthesis. This small protein has a molecular weight of approximately 14 kDa. RPS26 is widely expressed in various tissues indicating its functional importance in cellular processes. As a component of the 40S ribosomal subunit it plays a role in the translation process by contributing to the assembly and structure of the ribosome.
Biological function summary
RPS26 functions as a fundamental component of the ribosome where it interacts with ribosomal RNA and other ribosomal proteins to facilitate protein synthesis. This protein is part of the ribonucleoprotein complex essential for translating mRNA into polypeptides. The involvement of RPS26 in the intricate ribosomal machinery ensures the accurate and efficient production of cellular proteins that drive numerous cellular activities.
Pathways
RPS26 contributes significantly to protein synthesis pathways notably engaging in the translation initiation pathway. In this pathway RPS26 closely interacts with other ribosomal proteins such as RPS20 and RPS21. Its involvement in ribosome biogenesis pathways also plays a critical role in cellular growth and proliferation further connecting its function to essential cellular processes.
Mutations or disruptions in RPS26 can be associated with Diamond-Blackfan Anemia a disorder that affects red blood cell production. This connection highlights the sensitivity of erythropoiesis to perturbations in ribosomal function. Additionally changes in RPS26 expression levels also hint at its potential involvement in various cancers where it might interact with proteins like MDM2 influencing tumor suppression pathways.