Abcam, ab235455, OSMI-1, O-GlcNAc transferase (OGT) inhibitor

Size: 5mg / 25mg
MW 563.6 Da, Purity >98%. Potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor. Inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
Key facts
CAS number:1681056-61-0,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:563.6 Da,
Molecular formula:C28H25N3O6S2,
PubChem:118634407,
Nature:Synthetic,
Solubility:DMSO ~20 mg/mL,
Biochemical name:(R)-N-(furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-(2-oxo-1,2-dihydroquinoline-6-sulfonamido)-N-(thiophen-2-ylmethyl)acetamide,
Biological description:Potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor. Inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.,
Canonical smiles:COC1=CC=CC=C1C(C(=O)N(CC2=CC=CO2)CC3=CC=CS3)NS(=O)(=O)C4=CC5=C(C=C4)NC(=O)C=C5,
Isomeric smiles:COC1=CC=CC=C1[C@H](C(=O)N(CC2=CC=CO2)CC3=CC=CS3)NS(=O)(=O)C4=CC5=C(C=C4)NC(=O)C=C5,
InChi:InChI=1S/C28H25N3O6S2/c1-36-25-9-3-2-8-23(25)27(28(33)31(17-20-6-4-14-37-20)18-21-7-5-15-38-21)30-39(34,35)22-11-12-24-19(16-22)10-13-26(32)29-24/h2-16,27,30H,17-18H2,1H3,(H,29,32)/t27-/m1/s1,
InChiKey:IYIGLWQQAMROOF-HHHXNRCGSA-N,
IUPAC Name:(2R)-N-(furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-[(2-oxo-1H-quinolin-6-yl)sulfonylamino]-N-(thiophen-2-ylmethyl)acetamide

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B1916 OSMI-1. B1916-5 is the same size as the 5 mg size of ab235455.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions