Cytiva Cell Culture & Fermentation Solutions for Bioprocessing

Cytiva’s Cell Culture & Fermentation portfolio includes bioreactors, single-use systems, media, and essential equipment designed for scalable cell culture, microbial fermentation, and process development. Widely used in biopharmaceutical production, cell therapy, and protein expression, Cytiva solutions deliver reliable performance, GMP compliance, and trusted support to advance your research and manufacturing goals.

Explore Cytiva Cell Culture & Fermentation Products

Discover a complete range of Cytiva cell culture and fermentation products engineered for upstream bioprocessing. Whether you need flexible single-use bioreactors, reliable cell culture media, or robust microbial fermentation systems, Cytiva provides proven solutions to streamline scale-up and manufacturing. Explore the main categories below to find the right tools for your workflow.

Why Choose Cytiva for Cell Culture and Fermentation?

Selecting Cytiva for your cell culture and fermentation needs means choosing industry-leading innovation, proven GMP compliance, and reliable support. Cytiva combines decades of bioprocessing expertise with rigorous quality standards, helping you accelerate development, maximize yields, and ensure safety at every stage. Whether scaling up antibody production or launching new cell therapies, Cytiva solutions empower you to meet demanding regulatory and operational goals with confidence.

Key Advantages of Cytiva Cell Culture & Fermentation Products:

• Cutting-edge Bioprocess Innovation: Advanced bioreactor designs, single-use technologies, and scalable solutions for every workflow.

• GMP Compliance & Quality Assurance: Products manufactured under strict quality systems, supporting regulatory approvals and reproducibility.

• Comprehensive Technical Support: Global service network and expert consultation to troubleshoot, optimize, and validate your processes.

• Proven Reliability: Trusted by top biopharmaceutical manufacturers and research institutions worldwide for consistent performance.

• Flexible, Scalable Solutions: From R&D labs to commercial production, Cytiva systems are designed for seamless process transfer and expansion.

As your workflows grow more complex, Cytiva’s integrated technologies and support services help you unlock new possibilities in bioprocessing, cell therapy, and beyond.

Key Applications in Bioprocessing and Cell Therapy

Cytiva’s cell culture and fermentation solutions are trusted across a wide range of bioprocessing and cell therapy applications. No matter your workflow stage or production scale, you’ll find proven systems and consumables optimized for efficiency, quality, and regulatory success. Explore the most common use cases below:

• Antibody Production
  Achieve high yields and consistent quality in monoclonal antibody manufacturing with scalable bioreactor platforms and optimized cell culture media.

• Protein Expression
  Support recombinant protein production in both mammalian and microbial systems, from laboratory research to commercial manufacturing.

• Cell Therapy Manufacturing
  Enable large-scale expansion of therapeutic cell lines, including CAR-T and stem cells, with GMP-compliant single-use systems and robust monitoring solutions.

• Microbial Fermentation
  Drive efficient microbial fermentation for enzyme, vaccine, and metabolite production using advanced fermentors and process control technologies.

• Vaccine Development
  Accelerate upstream process development and scale-up for viral and protein-based vaccines with flexible bioprocess equipment and expert support.

No matter your application, Cytiva delivers reliable performance and regulatory peace of mind, allowing you to focus on advancing your science.

Featured Cytiva Bioreactors, Media & Equipment

Explore a curated selection of Cytiva’s top-performing bioreactors, cell culture media, and essential fermentation equipment. Each product is engineered for consistent results in antibody production, protein expression, and cell therapy manufacturing.

How to Select the Right Cytiva Bioreactor or Cell Culture Media

Choosing the ideal bioreactor or cell culture media is essential for maximizing cell growth, yield, and process efficiency. Cytiva offers a wide range of solutions, including single-use and traditional systems, to support various cell lines, process scales, and bioproduction goals. Use the following guide to identify the best-fit products for your application:

1. Match Bioreactor Type to Cell Line and Process

• For mammalian cell culture (e.g., CHO, HEK293), consider Xcellerex™ XDR-10 (SKU: 28963864) or WAVE Bioreactor™ 20/50 EHT (SKU: 28936255) for gentle mixing and scalability.

• For microbial fermentation (e.g., E. coli, yeast), modular systems like Applikon MiniBio (SKU: APGMBIO) offer precise control and flexibility at lab scale.

2. Scale Up with Confidence

• Select a bioreactor volume that supports your current needs but also enables seamless scale-up. Xcellerex™ XDR series covers pilot to commercial scale, while Xuri™ Cell Expansion System W25 (SKU: 28912456) is designed for cell therapy process development.

3. Optimize Media for Cell Type and Productivity

• HyClone™ ActiPro Medium (SKU: SH31028.02) and HyClone™ SFM4CHO Media (SKU: SH30551.02) are optimized for CHO cells and recombinant protein expression.

• Use chemically defined, serum-free media to minimize variability and support regulatory compliance in GMP production.

4. Common Mistakes to Avoid

• Using research-grade media in clinical or GMP manufacturing—always verify media qualifications and certifications.

• Overlooking compatibility between bioreactor, bags, and control systems—ensure components (e.g., Xcellerex™ XDA Disposable Assemblies, SKU: 29133650) are designed to work together.

5. Practical Tips

• Consult Cytiva’s technical team for process-specific recommendations and validation support.

• Start with small-scale or benchtop trials (e.g., Applikon MiniBio) before scaling up to larger platforms.

• Document your process parameters to ensure reproducibility and regulatory traceability.

Selecting the right Cytiva solutions helps you maximize cell viability, product yield, and process robustness across research, clinical, and commercial settings.

FAQs on Cytiva Cell Culture and Fermentation Solutions

1. Are Cytiva cell culture and fermentation systems GMP-compliant?

Yes. Most Cytiva bioreactors, media, and single-use assemblies—including the Xcellerex™ and WAVE Bioreactor™ series—are designed and manufactured under strict quality systems to support cGMP production, regulatory compliance, and full process documentation.

2. Which cell types and applications are supported?

Cytiva’s solutions are optimized for a broad spectrum of applications, including mammalian (e.g., CHO, HEK293), microbial (e.g., E. coli, yeast), insect, and stem cell cultures. Systems are widely used in antibody and protein production, cell therapy, vaccine manufacturing, and microbial fermentation.

3. What volume and configuration options are available?

Cytiva offers a complete range of scalable options, from benchtop (250 mL, 2 L) and lab-scale (10 L, 50 L) to pilot and commercial production volumes (up to 2000 L). Both single-use and traditional stainless steel formats are available to meet different process needs.