Abcam, ab120196, LY 379268, Group II mGlu agonist

Size: 10mg / 50mg
MW 187.15 Da, Purity >99%. Highly potent and systemically active mGlu 2 and mGlu 3 agonist. EC 50 values are 2.69 and 4.48 nM for hmGlu 2 and hmGlu 3 , respectively and displays >80-fold selectivity over group I and group III receptors. Effective in several animal models of stroke, epilepsy, drug abuse, schizophrenia, and pain.
Key facts
CAS number:191471-52-0,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:187.15 Da,
Molecular formula:C7H9NO5,
PubChem:10197984,
Nature:Synthetic,
Solubility:Soluble in water to 25 mM (with heating),
Biochemical name:(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid,
Biological description:Highly potent and systemically active mGlu2 and mGlu3 agonist. EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3, respectively and displays >80-fold selectivity over group I and group III receptors. Effective in several animal models of stroke, epilepsy, drug abuse, schizophrenia, and pain.,
Canonical smiles:C1C(C2C(C2O1)C(=O)O)(C(=O)O)N,
Isomeric smiles:C1[C@]([C@@H]2[C@H]([C@@H]2O1)C(=O)O)(C(=O)O)N,
InChi:InChI=1S/C7H9NO5/c8-7(6(11)12)1-13-4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1,
InChiKey:YASVRZWVUGJELU-MDASVERJSA-N,
IUPAC Name:(1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months