Abcam, ab120225, Harmine, DYRK1A inhibitor

Size: 100mg
MW 212.25 Da, Purity >98%. Potent and selective inhibitor of DYRK1A (dual specificity tyrosine-phosphorylated and -regulated kinase). (IC 50 values are 0.08 (DYRK1A), 0.9 (DYRK2), 0.8 (DYRK3), 4.3 (PIM3) and 1.5 μM (CK1)). 5-HT antagonist and MAO inhibitor. Regulator of PPARγ expression and antidiabetic.
Key facts
CAS number:442-51-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:212.25 Da,
Molecular formula:C13H12N2O,
PubChem:5280953,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Harmine,
Biological description:Potent and selective inhibitor of DYRK1A (dual specificity tyrosine-phosphorylated and -regulated kinase). (IC50 values are 0.08 (DYRK1A), 0.9 (DYRK2), 0.8 (DYRK3), 4.3 (PIM3) and 1.5 μM (CK1)). 5-HT antagonist and MAO inhibitor. Regulator of PPARγ expression and antidiabetic.,
Canonical smiles:CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC,
InChi:InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3,
InChiKey:BXNJHAXVSOCGBA-UHFFFAOYSA-N,
IUPAC Name:7-methoxy-1-methyl-9H-pyrido[3,4-b]indole

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months