Abcam, ab120289, TMCB, Selective CK2 inhibitor

Size: 10mg / 50mg
MW 534.82 Da, Purity >98%. CK2 inhibitor (K i = 0.25 μM), more selective than DMAT. Unlike DMAT, TMCB displays selectivity over PIM1, HIPK2 and DYRK1a (K i values are 8.65, 15.25 and 11.90 μM, respectively) and a more favourable selectivity profile over a range of other kinases.
Key facts
CAS number:905105-89-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:534.82 Da,
Molecular formula:C11H9Br4N3O2,
PubChem:46943415,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM (with heating),
Biochemical name:[4,5,6,7-Tetrabromo-2-(Dimethylamino)-1h-Benzimidazol-1-Yl]acetic Acid,
Biological description:CK2 inhibitor (Ki = 0.25 μM), more selective than DMAT. Unlike DMAT, TMCB displays selectivity over PIM1, HIPK2 and DYRK1a (Ki values are 8.65, 15.25 and 11.90 μM, respectively) and a more favourable selectivity profile over a range of other kinases.,
Canonical smiles:CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br,
InChi:InChI=1S/C11H9Br4N3O2/c1-17(2)11-16-9-7(14)5(12)6(13)8(15)10(9)18(11)3-4(19)20/h3H2,1-2H3,(H,19,20),
InChiKey:PHAOTASRLQMKBE-UHFFFAOYSA-N,
IUPAC Name:2-[4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazol-1-yl]acetic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months