Abcam, ab120306, HA-1077 (Fasudil), ROCK2 inhibitor

Size: 10mg / 50mg
MW 327.8 Da, Purity >98%. ROCK2 inhibitor (IC 50 = 1.9 μM). Also shown to inhibit PRK2 (IC 50 = 4 μM), MSK1 (IC 50 = 5 μM), Rsk2 (IC 50 = 15 μM), PKA, p70 S6 Kinase, CaM Kinase and MLCK. Calcium antagonist and vasodilator.
Key facts
CAS number:105628-07-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:327.8 Da,
Molecular formula:C14H18ClN3O2S,
PubChem:163751,
Nature:Synthetic,
Biochemical name:Fasudil hydrochloride,
Biological description:ROCK2 inhibitor (IC50 = 1.9 μM). Also shown to inhibit PRK2 (IC50 = 4 μM), MSK1 (IC50 = 5 μM), Rsk2 (IC50 = 15 μM), PKA, p70 S6 Kinase, CaM Kinase and MLCK. Calcium antagonist and vasodilator.,
Canonical smiles:C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl,
InChi:InChI=1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H,
InChiKey:LFVPBERIVUNMGV-UHFFFAOYSA-N,
IUPAC Name:5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months