Abcam, ab120331, FFN511, Fluorescent substrate for VMAT2

Size: 1mg / 5mg
MW 284.35 Da, Purity >98%. First novel fluorescent false neurotransmitter. Enables optical imaging of presynaptic terminal activity. Inhibits 5-HT binding to VMAT2 (IC 50 = 1 μM (comparable to dopamine itself)). Released via exocytosis in the striatum in mouse acute slice preparation. Labels dopamine and other presynaptic terminals in the striatum. Compatible with GFP tags and other optical probes. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy. View the technique online For highly selective labelling of dopaminergic presynaptic termainals FFN102 (ab120866) is recommended.
Key facts
CAS number:1004548-96-2,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:284.35 Da,
Molecular formula:C17H20N2O2,
PubChem:23725121,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 100 mM,
Biochemical name:False Fluorescent Neurotransmitter 511, FFN-511,
Biological description:First novel fluorescent false neurotransmitter. Enables optical imaging of presynaptic terminal activity.Inhibits 5-HT binding to VMAT2 (IC50 = 1 μM (comparable to dopamine itself)). Released via exocytosis in the striatum in mouse acute slice preparation. Labels dopamine and other presynaptic terminals in the striatum.Compatible with GFP tags and other optical probes. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy.View the technique onlineFor highly selective labelling of dopaminergic presynaptic termainals FFN102 (ab120866) is recommended.,
Canonical smiles:C1CC2=CC3=C(C4=C2N(C1)CCC4)OC(=O)C=C3CCN,
InChi:InChI=1S/C17H20N2O2/c18-6-5-11-10-15(20)21-17-13-4-2-8-19-7-1-3-12(16(13)19)9-14(11)17/h9-10H,1-8,18H2,
InChiKey:SKTIZSRPCXRDHX-UHFFFAOYSA-N,
IUPAC Name:6-(2-aminoethyl)-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2(7),5,8-tetraen-4-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months