Product Description
The TX17.10 monoclonal antibody recognizes the mouse protein TMTSP also known as THSD1, thrombospondin type-1 domain-containing protein, and transmembrane molecule with thrombospondin module. Mouse TMTSP has a predicted molecular weight of approximately 95 kD. TMTSP is a single pass, Type I transmembrane receptor that contains 1 thrombospondin-like domain. TMTSP is expressed on primitive hematopoietic stem cells and endothelial cells, but to date the function of this protein is unknown. The TX17.10 antibody has been shown to be useful for the detection of mouse TMTSP by flow cytometry, Western blotting, immunoprecipitation, and immunocytochemistry.
Product Details
25μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: mouse Tmtsp protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality testedWB, IP, ICC - Reported in the literature, not verified in house
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting, and immunocytochemistry.
Application References(PubMed link indicates BioLegend citation): Takayanagi S, et al. 2006. Blood 107:4317.
RRID: AB_830887 (BioLegend Cat. No. 122102)
Structure: Single pass, Type I transmembrane receptor, contains 1 thrombospondin-like domain
Distribution: Primitive hematopoietic stem cells and endothelial cells
Function: Unknown
Cell Type: Hematopoietic stem and progenitors, Endothelial cells
Biology Area: Immunology
Antigen References: 1. Takayanagi S, et al. 2006. Blood 107:4317.
Gene ID: 56229
UniProt: View information about TMTSP on UniProt.org
Clone: TX17.10
Regulatory Status: RUO
Other Names: THSD1, thrombospondin type-1 domain-containing protein, transmembrane molecule with thrombospondin module, predicted molecular weight approximately 95 kD
Isotype: Rat IgG2a, κ
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Collaboration
Tony Tang
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