Promega, JA1111, LAG-3/MHCII Blockade Bioassay

Measure Potency and Stability of Biologics Designed to Block LAG-3 Interactions
Prequalified according to ICH guidelines
96- and 384-well plate formats
No primary cell culture required
Supplied in convenient thaw-and-use format; also available in cell propagation model (CPM) format
Specifications：
LAG-3 Effector Cells J249A 1 × 0.5ml
MHCII APC Cells J250A 1 × 0.5ml
TCR Activating Antigen Stock Solution K120A 1 × 60μl
DMEM with 4.5g/L Glucose, L-Glutamine, Sodium Pyruvate J236A 1 × 60ml
Fetal Bovine Serum J121A 1 × 4ml
RPMI 1640 Medium G708A 1 × 36ml
Bio-Glo™ Luciferase Assay Buffer G719A 1 × 10ml
Bio-Glo™ Luciferase Assay Substrate G720A 1 × 1 vial
LAG-3 Effector Cells J249A 5 × 0.5ml
MHCII APC Cells J250A 5 × 0.5ml
TCR Activating Antigen Stock Solution K120A 5 × 60μl
DMEM with 4.5g/L Glucose, L-Glutamine, Sodium Pyruvate J236A 5 × 60ml
Fetal Bovine Serum J121A 5 × 4ml
RPMI 1640 Medium G708A 5 × 36ml
Bio-Glo™ Luciferase Assay Buffer G719A 5 × 10ml
Bio-Glo™ Luciferase Assay Substrate G720A 5 × 1 vial
LAG-3 Effector Cells (CPM) J245A 2 × 1ml
TCR Activating Antigen Stock Solution K120B 1 × 500μl
MHCII APC Cells (CPM) J246A 2 × 1ml
Control Ab, Anti-LAG-3 K115A 1 × 100μg
TCR Activating Antigen Stock Solution K120B 1 × 500μl