Sartorius, 20260-052, PPA HyperCel - 10 L

PPA HyperCel is a Mixed Mode resin with an aromatic ligand exhibiting stronger hydrophobicity and providing a different selectivity in protein purification.
Bulk resins offer flexibility and scalability for large-scale bioprocessing
Allow for customized column packing to meet specific process requirements

PPA HyperCel resin is an industry-scalable chromatography resin designed for protein capture and impurity removal in a biopharmaceutical environment. Operating on a “Mixed Mode” mechanism, with a phenlypropylamine ligand, its behavior is based on a combination of electrostatic and hydrophobic interactions of the proteins with the ligands. PPA HyperCel resin provides unique selectivities, different from those given by ion exchange or conventional HIC (hydrophobic interaction chromatography).
Bulk resins are available in various quantities to support different scaling processes, ensuring flexibility and adaptability. Perfect for large-scale purification processes.
Features and Benefits
High mechanical and chemical stability
Suitable for large-scale chromatography in a biopharmaceutical environment
Cross-linked cellulose base matrix
Applications
Protein purification at low ionic strength by direct hydrophobic capture
Separation of challenging mixtures, e.g. protein isoforms or proteins with very close pIs
Orthogonal separation mechanism to ion exchange or HIC

Specifications
Applications:
Application: Preparative protein purification

Compliance Information:
Quality Standards: CoA; RSF

Dimensions:
Bead Size: 80 - 100 µm

General Specifications:
Flow Rate: 100-600cm/h
Resin Format: Bulk resin

Materials of Construction:
Base Matrix: Rigid cellulose beads

Operating Conditions:
Operating Pressure: < 3 barg (44psi)
pH Stability: 1 to 14 (short term), 2 to 12 (long term)

Physicochemical Information:
Ligand: Phenylpropylamine
Reference Protein: Bovine serum albumin (BSA)
Typical Dynamic Binding Capacity 10% per mL: 40-60 mg/mL BSA

Product Information:
Brand: PPA HyperCel
Pack Size: 1
Pack Volume: 10 L
Resin Delivery Condition: 1M NaCl with 20% EtOH
Resin Type: Mixed Mode anion exchanger
What you receive: 1 bottle resin, instructions

Storage Conditions:
Storage Conditions: 20% EtOH/1M NaCl