Sartorius, 5237306D2--SO, Sartobran® P | MaxiCaps® | 0.45µm | 20"

Sartobran® P with its unique cellulose acetate (CA) membrane is mainly used for the sterile filtration of blood & plasma products as well as viral vaccines. The ultra-low binding feature of the membrane material leads to highest product yield. Especially large, shear-stress sensitive proteins do not lose their structure and function when filtered through this special membrane. This will improve your process output even further.

Sterilizing-Grade, 0.2 µm Rated Filters
Sartobran® P Pore size: 0.45 | 0.2 µm (CA double layer)
Your Benefits
High product yield due to ultra-low unspecific adsorption
Excellent filtration results especially for large, shear-stress sensitive proteins
Ideally suited for sterile filtration of viral vaccines and blood & plasma products
Sartobran® P filters are not suitable for gamma irradiation. For easy integration of non-gamma filters into single-use assemblies, we offer a wide range of possibilities with our Filter Transfer Set solutions.
For highest process flexibility Sartobran® P filters are available for conventional stainless-steel or single-use applications. The filter elements are available in various sizes and connector combinations. Please review the selection guide in the supporting literature.

Specifications
Applications:
Application: Blood and Plasma; Vaccine Production
Industry: Pharma / Biotech
Modality: Harvest | Cell Removal; Downstream Intermediates; Form & Fill
Scale: Production | Large Scale

Compliance Information:
Bacterial Endotoxins: < 0.25 EU/mL as determined by the LAL test
Biological Reactivity: All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
Extractables: The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Connections (Physical):
Connector Inlet: 1.5" Tri-clamp 50 mm
Connector Outlet: 1/2" Single Stepped Hose Barb
Connector(s): Inlet: 1 ½" Sanitary | Outlet: ½" Hose Barb

Dimensions:
Filter Size: 20"(1.2 m² / 12.9 ft²)
Filtration Area: 1.2 m² / 12.9 ft²
Outer Diameter: 137 mm (110 mm without Connection / Valves)

General Specifications:
Capsule/Cartridge Format: Maxicaps®
Maximum Allowable Back Pressure: 2 bar (29 psi) at 20°C; 1.5 bar (21.8 psi) at 50°C
Maximum Diffusion: 30 mL/min at 1.5 bar | 22 psi
Minimum Required Bubble Point: 2.0 bar | 29 psi
Vent Valve: Standard

Materials of Construction:
Housing Material: Polypropylene (PP)
Material o-ring | seal: Silicone (SI)
Membrane Material: Cellulose Acetate (CA)
Support Fleece: Polypropylene (PP)

Operating Conditions:
Maximum Differential Pressure: 20 °C: 5 bar, 50 °C: 3 bar
Maximum Operating Pressure: 5 bar (72.5 psi)

Physicochemical Information:
Non-Fiber Releasing: This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Pore Size Final-filter: 0.45 μm
Pore Size Pre-filter: 0.65 μm

Product Information:
Brand: Sartobran® P
Pack Size: 1
Type: Inline (Autoclavable)

Sterility/Purity:
Delivery Condition: Sterile - Autoclaved
Sterilization Method: Autoclavable

Usage Protocols:
Sterilization Procedures: Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles