Sartorius, PRCCMMHCEL5ML, CMM HyperCel PRC Column - 5 mL

CMM HyperCel is a hydrophobic cation exchanger designed for the capture of antibodies, antibody fragments, and recombinant proteins. It allows the separation of proteins with similar pIs and hydrophobicity by modulation of pH and conductivity.
Pre-packed columns simplify resin screening and selection
Ideal for process step optimization
RoboColumn® format is especially suited for high throughput process development (HTPD)

CMM HyperCel resin is composed of a rigid cellulose matrix that has flow properties compatible with the needs of manufacturing scale protein production.
The proprietary ligand, containing both a primary amine and a carboxyl group, confers cation exchange and hydrophobicity properties to the chromatography resin. The flexibility of the ligand enables the separation of proteins with a large variety of isoelectric points and hydrophobicity levels, and multiple conditions can be employed to separate targeted molecules from contaminants.
CMM HyperCel pre-packed columns are designed to simplify resin screening and selection, making them ideal for optimizing process steps. The RoboColumn® format is particularly suited for high throughput process development (HTPD), allowing for efficient and streamlined purification processes.
Features and Benefits
Unique selectivity
High capacity mixed-mode chromatography resin
High recovery, low elution volume
Easy CIP, NaOH stable
Applications
Capture of MAbs, Fab fragments and recombinant proteins from challenging feedstocks
Separation of proteins with similar isoelectric point and | or hydrophobicity at low or high conductivity

Specifications
Applications:
Application: Resin screening and process optimization

Compliance Information:
Quality Standards: CoA; RSF (upon request)

Dimensions:
Bead Size: 50 - 80 µm
Bed Height: 100 mm
Dimensions: 8 x 100 mm

General Specifications:
Flow Rate: 200-600cm/h
Resin Format: Pre-packed column

Materials of Construction:
Base Matrix: Rigid cellulose beads
Materials of Construction: Polypropylene

Operating Conditions:
Operating Pressure: < 3 barg (44psi)
pH Stability: 1 to 14 (short term), 2 to 13 (long term)

Physicochemical Information:
Bed Volume: 5 mL
Ligand: Aminobenzoic acid
Ligand Density: Av. 70 µeq/mL
Reference Protein: Bovine serum albumin (BSA); Human polyclonal IgG
Typical Dynamic Binding Capacity 10% per mL: > 50 mg/mL BSA at pH 4.5, 15 mS/cm; 60-100 mg/mL IgG at pH 4 to 5, 4-12 mS/cm

Product Information:
Brand: CMM HyperCel
Pack Size: 1 column per pack
Pack Volume: 5 mL
Resin Type: Mixed Mode cation exchanger
What you receive: 1 columnInstruction for use

Storage Conditions:
Storage Conditions: 20% EtOH/1M NaCl