Sartorius, PRCSTARAX1ML, HyperCel STAR AX PRC Column - 1 mL

HyperCel Star AX is a salt-tolerant anion exchanger with a primary amine as functional group. It can easily be integrated into a purification workflow without feed stream manipulation.

HyperCel STAR AX is an industry-scalable anion exchange chromatography resin designed for high productivity protein capture at moderate or higher salt conductivity (2 to 15 mS/cm), typical of undiluted biological feedstocks (e.g. mammalian cell culture supernatants, E. coli feedstock, plasma, etc.).
Features and Benefits
- High dynamic binding capacity (DBC) at short residence time (2 minutes or lower)
- Direct capture of protein from undiluted feedstock at moderate or high conductivity
- Excellent flow rate properties for fast feedstock processing
- Distinctive selectivity, consistent in a broad conductivity range (2 – 15 mS/cm)
- Enhanced process economics
- Manufactured at large scale and to meet the demands of commercial users and regulatory authorities
Applications
- Direct capture of recombinant proteins, mono- and poly-clonal antibodies, plasma derivatives
- Direct Capture of Albumin from Undiluted Plasma
- Early Removal of CHOPs before Protein A Capture of a Monoclonal Antibody (MAb)

Specifications
Applications:
Application: Resin screening and process optimization

Compliance Information:
Quality Standards: CoA

Dimensions:
Bead Size: 60 - 90 µm
Bed Height: 50 mm
Dimensions: 5 x 50 mm

General Specifications:
Flow Rate: 100-300cm/h
Resin Format: Pre-packed column

Materials of Construction:
Base Matrix: Rigid cellulose beads
Materials of Construction: Polypropylene

Operating Conditions:
Operating Pressure: < 3 barg (44psi)
pH Stability: 1 to 14 (short term), 2 to 12 (long term)

Physicochemical Information:
Bed Volume: 1 mL
Ligand: Primary amine (PA)
Reference Protein: Bovine serum albumin (BSA)
Typical Dynamic Binding Capacity 10% per mL: > 100 mg/mL BSA at pH 7.5 to 8.0 and conductivity to 15 mS/cm

Product Information:
Brand: HyperCel STAR AX
Pack Size: 1 column per pack
Pack Volume: 1 mL
Resin Delivery Condition: 1M NaCl with 20% EtOH
Resin Type: Ion Exchange
What you receive: 1 column, instructions

Storage Conditions:
Storage Conditions: 20% EtOH/1M NaCl