Abcam, ab108349, Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal

Size: 20µL / 100µL / 1mL
Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) is a rabbit monoclonal antibody detecting CDKN2A/p16INK4a in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IP, IHC-P . Suitable for Human . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency - Over 190 publications
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR1473,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IP, IHC-P, WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:Expression levels of the CDKN2A/p16INK4a protein may vary with sample type. It is barely expressed in normal tissue, and mostly expressed in some tumour tissues, such as cervical cancer, breast cancer and so on. Moreover, only expressed in some cell lines. Please see images for recommended positive controls.

Product details:
Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), IHC-P, IP and WB.
Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) was first used in a scientific publication in 2013 and has been cited over 192 times in peer reviewed journals. It's performance in Western Blot and IHC in human samples is trusted by the scientific community.
Abcam's high quality manufacturing and validation processes ensure Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
The specificity of Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) has been confirmed by Western Blot testing in CDKN2A/p16INK4a knockout HEK-293T cells.
Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) has 6 independent reviews from customers.
Anti-CDKN2A/p16INK4a antibody [EPR1473] - C-terminal (ab108349) specifically detects CDKN2A/p16INK4a (UniProt ID: P42771; Molecular weight: 17kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL).
Conjugation-ready, carrier free format available for antibody clone EPR1473 -
ab186932
Antibody clone EPR1473 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor
647, PE (
ab192054
ab209579
CDKN2A, encoding the tumor suppressor protein p16INK4a, plays a crucial role in regulating the cell cycle by inhibiting cyclin-dependent kinases, thereby preventing uncontrolled cell proliferation. Mutations or deletions in CDKN2A are frequently associated with various cancers, including melanoma, pancreatic cancer and head and neck squamous cell carcinoma.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle