Abcam, ab109012, Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker

Size: 100µL / 1mL
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) is a rabbit monoclonal antibody detecting SQSTM1 / p62 in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IP, ICC/IF . Suitable for Human, Mouse, Rat . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency - Over 440 publications
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR4844,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:WB, ICC/IF, Flow Cyt (Intra), IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:This antibody got too weak band in rat tissues, you may need to optimize experimental protocols (increasing lysate amount, using lower dilution or higher sensitivity ECL substrate) to get visible band. However, it performs very well in rat cell lines.

Product details:
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IP and WB.
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) was first used in a scientific publication in 2014 and has been cited over 445 times in peer reviewed journals. It's performance in Western Blot in human, mouse and rat samples is trusted by the scientific community.
Abcam's high quality manufacturing and validation processes ensure Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
The specificity of Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) has been confirmed by Western Blot testing in SQSTM1 / p62 knockout HEK-293T cells (
ab263770
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) has 15 independent reviews from customers.
Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) specifically detects SQSTM1 / p62 (UniProt ID: Q13501; Molecular weight: 48kDa) and is sold in 100 µL and 1 mL selling sizes.
Conjugation-ready, carrier free format available for antibody clone EPR4844 -
ab219581
Antibody clone EPR4844 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, HRP, Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 555, APC, PE (
ab185015
ab194720
ab194721
ab203429
ab203430
ab225093
ab225094
NEW: Explore our alternative host species for clone [EPR4844] : goat. SQSTM1, also known as p62, is a multifunctional scaffolding protein widely used in neuro research for its role in autophagy and protein degradation. It is upregulated in several neurodegenerative disorders, including Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). Researchers use SQSTM1/p62 to study the mechanisms of protein aggregation and neuroinflammation, making it essential for understanding the progression of neurodegenerative diseases and identifying potential therapeutic targets.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Shipping conditions update: ambient shipping
This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality.
Why the change?
It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene.
What you need to know
Ambient shipments come clearly marked on the delivery note.
No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products.
Warranty coverage remains fully valid, aligned with our validated shipping method.
Please store the product as per the datasheet instructions upon receipt.
Find out more -
https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Conditional Ambient, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Stable for 12 months at -20°C