Abcam, ab120364, NNC 711, GAT-1 inhibitor

Size: 10mg / 50mg
MW 386.9 Da, Purity >99%. Potent and selective GAT-1 GABA uptake inhibitor. (IC 50 values are 0.04 (hGAT-1), 171 (rGAT-2), 1700 (hGAT-3) and 622 μM (hBGT-1)). Selective over a range of other neurotransmitter receptor binding sites, uptake sites and ion channels in vitro . Potent anticonvulsant, neuroprotectant and cognitive enhancer in vivo . Also available in simple stock solutions (ab146719) - add 1 ml of water to get an exact, ready-to-use concentration.
Key facts
CAS number:145645-62-1,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:386.9 Da,
Molecular formula:C21H23ClN2O3,
PubChem:123738,
Nature:Synthetic,
Solubility:Soluble in water to 10 mM,
Biochemical name:1-(2-(((Diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid,
Biological description:Potent and selective GAT-1 GABA uptake inhibitor. (IC50 values are 0.04 (hGAT-1), 171 (rGAT-2), 1700 (hGAT-3) and 622 μM (hBGT-1)). Selective over a range of other neurotransmitter receptor binding sites, uptake sites and ion channels in vitro. Potent anticonvulsant, neuroprotectant and cognitive enhancer in vivo.Also available in simple stock solutions (ab146719) - add 1 ml of water to get an exact, ready-to-use concentration.,
Canonical smiles:C1CN(CC(=C1)C(=O)O)CCON=C(C2=CC=CC=C2)C3=CC=CC=C3.Cl,
InChi:InChI=1S/C21H22N2O3.ClH/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18;/h1-6,8-12H,7,13-16H2,(H,24,25);1H,
InChiKey:YZYRTEYMUTWJPL-UHFFFAOYSA-N,
IUPAC Name:1-[2-(benzhydrylideneamino)oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months