Abcam, ab120497, Bafilomycin A1, (V)-ATPase inhibitor

Size: 10µg / 100µg
MW 622.8 Da. Highly potent, selective vacuolar (V)-ATPase inhibitor (IC 50 = 500 pM in chromaffin granule membranes). Induces vacuolar deacidification and promotes apoptosis.
Key facts
CAS number:88899-55-2,
Form:SolidSee storage information,
Source:Streptomyces griseus,
Molecular weight:622.8 Da,
Molecular formula:C35H58O9,
PubChem:6436223,
Nature:Native,
Solubility:Soluble in ethanol to 5mM,
Biochemical name:bafilomycin A1,
Biological description:Highly potent, selective vacuolar (V)-ATPase inhibitor (IC50 = 500 pM in chromaffin granule membranes). Induces vacuolar deacidification and promotes apoptosis.,
Canonical smiles:CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)O)O)O)OC)C,
Isomeric smiles:C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C,
InChi:InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12+,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33+,35+/m0/s1,
InChiKey:XDHNQDDQEHDUTM-JQWOJBOSSA-N,
IUPAC Name:(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months