Abcam, ab120558, PNU 282987, alpha7 nAChR agonist

Size: 10mg / 50mg
MW 301.2 Da, Purity >99%. Selective α7nAChR agonist. Negligible activity at α1β1γδ and α3β4 receptors. High affinity for rat α7nACh receptors (K i = 26 nM). Functional antagonist at 5-HT 3 receptors (IC 50 = 4541 nM).
Key facts
CAS number:123464-89-1,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:301.2 Da,
Molecular formula:C14H18Cl2N2O,
PubChem:11243536,
Nature:Synthetic,
Solubility:Soluble in water to 100 mM,
Biochemical name:Benzamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-4-chloro-, hydrochloride (1:1),
Biological description:Selective α7nAChR agonist. Negligible activity at α1β1γδ and α3β4 receptors. High affinity for rat α7nACh receptors (Ki = 26 nM). Functional antagonist at 5-HT3 receptors (IC50 = 4541 nM).,
Canonical smiles:C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl.Cl,
Isomeric smiles:C1CN2CCC1[C@H](C2)NC(=O)C3=CC=C(C=C3)Cl.Cl,
InChi:InChI=1S/C14H17ClN2O.ClH/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17;/h1-4,10,13H,5-9H2,(H,16,18);1H/t13-;/m0./s1,
InChiKey:HSEQUIRZHDYOIX-ZOWNYOTGSA-N,
IUPAC Name:N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months