Abcam, ab120581, A-412997 dihydrochloride, D4 agonist

Size: 10mg / 50mg
MW 382.33 g/mol, Purity >98%. Highly selective dopamine D 4 receptor agonist at rat D 4 and human D 4.4 receptors (K i values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D 4 receptors (EC 50 = 28.4 nM). Superior selectivity profile to PD168077 (ab120568) and CP226269. No affinity for other dopamine receptors (K i > 1 μM). Able to rapidly cross the blood-brain barrier following systemic administration.
Key facts
CAS number:1347744-96-0,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:382.33 g/mol,
Nature:Synthetic,
Solubility:Soluble in water to 100 mM,
Biological description:Highly selective dopamine D4 receptor agonist at rat D4 and human D4.4 receptors (Ki values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D4 receptors (EC50 = 28.4 nM). Superior selectivity profile to PD168077 (ab120568) and CP226269. No affinity for other dopamine receptors (Ki > 1 μM). Able to rapidly cross the blood-brain barrier following systemic administration.,
IUPAC Name:N-(3-Methylphenyl)-2-[4-(2-pyridinyl)-1-piperidinyl]acetamide dihydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months