Abcam, ab120858, SCH79797 dihydrochloride, PAR1 antagonist

Size: 10mg / 50mg
MW 444.4 Da, Purity >98%. Potent and selective non-peptide Proteinase-Activated Receptor-1 (PAR1) antagonist (IC50 = 70 nM). Protects against ischemic injury. Additionally induces apoptosis and inhibits cell proliferation.
Key facts
CAS number:245520-69-8,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:444.4 Da,
Molecular formula:C23H27Cl2N5,
PubChem:45073452,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mMSoluble in ethanol to 10 mM,
Biochemical name:SCH 79797 dihydrochloride,
Biological description:Potent and selective non-peptide Proteinase-Activated Receptor-1 (PAR1) antagonist (IC50 = 70 nM). Protects against ischemic injury. Additionally induces apoptosis and inhibits cell proliferation.,
Canonical smiles:CC(C)C1=CC=C(C=C1)CN2C=CC3=C2C=CC4=C3C(=NC(=N4)NC5CC5)N.Cl.Cl,
InChi:InChI=1S/C23H25N5.2ClH/c1-14(2)16-5-3-15(4-6-16)13-28-12-11-18-20(28)10-9-19-21(18)22(24)27-23(26-19)25-17-7-8-17;;/h3-6,9-12,14,17H,7-8,13H2,1-2H3,(H3,24,25,26,27);2*1H,
InChiKey:NNJTXSQXGHYXAJ-UHFFFAOYSA-N,
IUPAC Name:3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine;dihydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months