Abcam, ab120866, FFN102 (Mini 102), Fluorescent DAT and VMAT2 substrate

Size: 5mg
MW 353.68 Da, Purity >98%. Novel, pH responsive fluorescent false neurotransmitter (FFN). Rodent DAT and VMAT2 substrate. Enables two-photon microscopic imaging of localization and activity of dopaminergic presynaptic terminals in the striatum of mouse acute brain slice. More selective for dopaminergic synapses than FFN511 (ab120331). Exhibits greater fluorescence emission in neutral than acidic environments allowing optical measurement of synaptic vesicle content release. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy and standard fluorescent microscopy. Compatible with GFP tags.
Key facts
CAS number:1234064-11-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:353.68 Da,
Molecular formula:C13H11ClF3NO5,
PubChem:91885430,
Nature:Synthetic,
Solubility:Soluble in water to 50 mM,
Biochemical name:4-(2-Aminoethyl)-6-chloro-7-hydroxychromen-2-one;2,2,2-trifluoroacetic acid,
Biological description:Novel, pH responsive fluorescent false neurotransmitter (FFN). Rodent DAT and VMAT2 substrate. Enables two-photon microscopic imaging of localization and activity of dopaminergic presynaptic terminals in the striatum of mouse acute brain slice. More selective for dopaminergic synapses than FFN511 (ab120331).Exhibits greater fluorescence emission in neutral than acidic environments allowing optical measurement of synaptic vesicle content release.Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy and standard fluorescent microscopy. Compatible with GFP tags.,
Canonical smiles:C1=C(C2=CC(=C(C=C2OC1=O)O)Cl)CCN.C(=O)(C(F)(F)F)O,
InChi:InChI=1S/C11H10ClNO3.C2HF3O2/c12-8-4-7-6(1-2-13)3-11(15)16-10(7)5-9(8)14;3-2(4,5)1(6)7/h3-5,14H,1-2,13H2;(H,6,7),
InChiKey:OGHPXKAKVMJGQH-UHFFFAOYSA-N,
IUPAC Name:4-(2-aminoethyl)-6-chloro-7-hydroxychromen-2-one;2,2,2-trifluoroacetic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months