Abcam, ab120889, Tenovin-1, p53 Activator

Size: 10mg / 50mg
MW 369.48 g/mol, Purity >98%. p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro .
Key facts
CAS number:380315-80-0,
Purity:>98%,
Molecular weight:369.48 g/mol,
Molecular formula:C20H23N3O2S,
Nature:Synthetic,
Solubility:Soluble in DMSO to 0.25 mg/ml,
Biological description:p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro.,
Canonical smiles:CC(=O)NC1CCC(CC1)NC(=S)NC(=O)C1CCC(CC1)C(C)(C)C,
IUPAC Name:N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl-4-(1,1-dimethylethyl)]benzamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months