Abcam, ab120898, AS-041164, PI3K gamma inhibitor

Size: 5mg / 25mg
MW 249.24 g/mol, Purity >98%. Potent PI3K inhibitor with selectivity for PI3Kγ (IC 50 = 70 nM), compared to PI3Kα, β and δ (IC 50 values are 240 nM, 1.45 and 1.70 μM, respectively). Shows little or n o activity against 38 other common kinases. Blocks neutrophil migration. Active in vivo .
Key facts
CAS number:6318-41-8,
Purity:>98%,
Molecular weight:249.24 g/mol,
Molecular formula:C11H7NO4S,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biological description:Potent PI3K inhibitor with selectivity for PI3Kγ (IC50 = 70 nM), compared to PI3Kα, β and δ (IC50 values are 240 nM, 1.45 and 1.70 μM, respectively). Shows little or n o activity against 38 other common kinases. Blocks neutrophil migration. Active in vivo.,
Isomeric smiles:O=C(/C(S1)=C/C2=CC=C3C(OCO3)=C2)NC1=O,
IUPAC Name:5-[(1,3-Benzodioxol-5-yl)methylene]-2,4-thiazolidinedione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months