Abcam, ab120939, DRB (Benzimidazole), Casein kinase II inhibitor

Size: 10mg / 50mg
MW 319.14 g/mol, Purity >98%. Casein kinase II inhibitor (K i values are 23 and 48 μM for CKII and CKI, respectively). Inhibitor of RNA polymerase II transcription in vitro and in vivo . Shown to inhibit cyclin C/CDK8 (IC 50 = 17 μM) and cyclin H/CDK7/p38 (IC 50 = 18 μM) signaling.
Key facts
CAS number:53-85-0,
Purity:>98%,
Molecular weight:319.14 g/mol,
Molecular formula:C12H12Cl2N2O4,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biological description:Casein kinase II inhibitor (Ki values are 23 and 48 μM for CKII and CKI, respectively). Inhibitor of RNA polymerase II transcription in vitro and in vivo. Shown to inhibit cyclin C/CDK8 (IC50 = 17 μM) and cyclin H/CDK7/p38 (IC50 = 18 μM) signaling.,
Isomeric smiles:OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CNC2CC(CL)C(CL)CC12,
IUPAC Name:5,6-Dichloro-1-β-D-ribofuranosyl-1H-benzimidazole

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months