Abcam, ab122510, Anti-TMEM164 antibody

Size: 100µL
Rabbit Polyclonal TMEM164 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM164 aa 1-50.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human TMEM164 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.Q5U3C3

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
TMEM164 also known as Transmembrane Protein 164 is a protein that plays a role in cellular mechanisms. It has a molecular mass of about 42 kDa. TMEM164 integrates into cellular membranes with several transmembrane domains contributing to various membrane-associated processes. The protein sees expression across multiple tissues with higher levels observed in areas such as the brain and immune cells suggesting specialized roles in these tissues.
Biological function summary
TMEM164 contributes to the regulation of cellular processes and is associated with complexes that facilitate signal transduction. It might take part in cellular adhesion by influencing the interactions between cells and the extracellular matrix. This can be important for maintaining tissue structure and cellular communication underpinning several physiological functions.
Pathways
TMEM164 interacts functionally within key cellular pathways including the Wnt signaling pathway. In this context it affects cellular proliferation and differentiation processes essential for development and repair mechanisms. Its role may intersect with proteins like β-catenin a critical factor in Wnt signaling indicating a collaborative influence in pathway modulation.
Research links TMEM164 to conditions such as cancer and neurodegenerative disorders. Dysregulation of TMEM164 expression or function may contribute to abnormal cellular proliferation or loss of neuronal integrity. The protein's interactions with key regulators in these disease contexts such as alterations in β-catenin in cancer show its potential impact on disease pathways and make it a target of interest for therapeutic intervention strategies.