Abcam, ab124994, Anti-Elongation factor 1-gamma antibody [EPR7200]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal Elongation factor 1-gamma antibody. Suitable for IHC-P, WB, ICC/IF, Flow Cyt (Intra) and reacts with Human, Mouse, Rat samples. Cited in 3 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR7200,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:Flow Cyt (Intra), ICC/IF, IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Elongation factor 1-gamma sometimes called EF-1γ is a protein that plays an important role in the process of protein biosynthesis. It is part of the elongation factor complex essential for the elongation phase of translation. This protein has a molecular weight of about 50 kDa. EF-1γ is expressed ubiquitously meaning it is found in many different types of tissues throughout the body indicating its broad necessity for cellular function.
Biological function summary
Elongation factor 1-gamma supports the stability and functionality of the larger elongation factor 1 complex which also includes EF-1 alpha EF-1 beta and EF-1 delta. This complex facilitates the economic and rapid engagement of aminoacyl-tRNA to the ribosome's A-site which is important in the synthesis of proteins ensuring that proteins are accurately and efficiently elongated during translation.
Pathways
Elongation factor 1-gamma has significance in the translation pathway and is also linked to the mTOR signaling pathway. The translation pathway is fundamental for general protein synthesis while the mTOR pathway is pivotal in regulating cell growth and proliferation. In these contexts elongation factor 1-gamma associates with other proteins such as elongation factor 1 alpha to optimize the elongation step of protein synthesis impacting cell growth and survival.
Elongation factor 1-gamma shows connections to certain cancer types and neurodegenerative diseases. In cancer alterations or dysregulations of EF-1γ expression can influence tumor growth and development. Meanwhile relation to neurodegenerative disorders is under study as EF-1γ participates in protein synthesis with possible impacts on neuronal survival. Elongation factor 1-gamma’s interactions with proteins like EF-1 alpha in these conditions spotlight its importance to cellular homeostasis and pathology.