Abcam, ab126337, Anti-C6orf129 antibody

Size: 100µL
Rabbit Polyclonal C6orf129 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CCDC167.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human CCDC167. The exact immunogen used to generate this antibody is proprietary information.Q9P0B6

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C6orf129 also known as chromosome 6 open reading frame 129 is a protein that plays a role in cellular signaling processes. It has a mass of approximately 69 kDa. Expression of C6orf129 occurs in various tissues with higher levels found in brain and reproductive organs. Researchers are still exploring the full mechanical action of C6orf129 but it is thought to participate in signal transduction pathways that regulate cell functions.
Biological function summary
This protein contributes to the modulation of neurobiological processes and has been associated with cellular communication activities. It does not typically form part of a known complex but its role in neuron cell signaling suggests a synergistic effect with other signaling proteins. Studies indicate potential involvement in synaptic plasticity hinting at functions related to nerve signal transmission.
Pathways
C6orf129 influences synaptic signaling and brain development pathways. It interacts with proteins such as synaptotagmin and neurotrophin receptors which play significant roles in these pathways. Through these interactions C6orf129 helps regulate synaptic connectivity and neuron growth suggesting its importance in nervous system maintenance.
Researchers have linked altered expression of C6orf129 to neurological conditions like schizophrenia and epilepsy. Abnormal levels of this protein could affect neurotransmitter systems potentially contributing to the symptoms observed in these disorders. It stands in relation to proteins like dopamine receptor D2 and alpha-synuclein known for their involvement in neurological pathologies further highlighting its relevance in disease mechanisms.