Abcam, ab126512, Anti-C16orf88 antibody

Size: 100µL
Rabbit Polyclonal C16orf88 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human KNOP1 aa 350 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human KNOP1 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q1ED39

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C16orf88 also known as Chromosome 16 Open Reading Frame 88 is an uncharacterized protein that plays a role at the cellular level. With a molecular mass of approximately 44 kDa C16orf88 is expressed in various tissues with substantial expression in the brain and testis. Its exact functions are not fully understood but research suggests it may participate in cellular structural frameworks or signaling pathways due to its presence across different cell types.
Biological function summary
The protein influences cellular processes by contributing to the regulation of cell cycle or structural integrity. Current studies indicate that C16orf88 might form part of a multiprotein complex which supports its role in maintaining cellular organization or facilitating communication between signaling molecules. Although information remains limited C16orf88's expression pattern suggests it may affect cellular differentiation and developmental biology particularly in neural tissues.
Pathways
Existing evidence connects C16orf88 to neurological and reproductive pathways. It may join key components of MAPK/ERK signaling pathways and demonstrate interactions with proteins such as ERK1/2 which are known regulators of cell division and differentiation. Participation in these pathways positions C16orf88 as a contributor to signal transduction that affects overall physiological responses and developmental processes.
C16orf88 shows potential linkage with neurodegenerative diseases and reproductive health issues. Disruption in its function or expression has associations with conditions like Alzheimer's disease where proteins such as TAU related to C16orf88 play a central role in disease progression. Similarly abnormal activity can trigger reproductive disorders by affecting related proteins involved in testicular function though precise mechanisms and pathways require further research for clarity.