Abcam, ab133701, Anti-HOXB9 antibody [EPR6950]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal HOXB9 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR6950,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
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contact us
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Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The HOXB9 protein also known as homeobox B9 acts as a transcription factor. This protein has a role in regulating gene expression during development. HOXB9 weighs approximately 27 kDa and it finds expression mainly in the lungs digestive system and hematopoietic cells. As part of the homeobox gene family HOXB9 contributes to the proper development and differentiation of tissues.
Biological function summary
HOXB9 helps regulate the growth and development of tissues and organs. It does not function alone but is part of a larger group of homeobox genes all of which work together for normal morphological development. This protein provides specificity in binding DNA sequences which in turn controls the expression of genes necessary for organogenesis.
Pathways
HOXB9 plays a role in the Wnt signaling pathway and the hedgehog signaling pathway. These pathways are essential for proper embryonic development. Within these pathways HOXB9 interacts with other proteins like β-catenin and Gli proteins supporting the regulation of cellular proliferation and differentiation.
HOXB9 shows a significant relation to breast cancer and lung adenocarcinoma. In these cancers HOXB9 expression levels often increase contributing to tumor progression. This protein interacts with others involved in cancer pathways such as VEGF and MMPs promoting angiogenesis and metastasis. Researchers closely study HOXB9 as a potential target for therapeutic intervention in such malignancies.