Abcam, ab134916, Anti-TAF15 antibody [EPR9197(B)]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal TAF15 antibody. Suitable for IHC-P, WB, ICC/IF, Flow Cyt (Intra) and reacts with Human samples. Cited in 25 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR9197(B),
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, IHC-P, ICC/IF, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Shipping conditions update: ambient shipping
This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality.
Why the change?
It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene.
What you need to know
Ambient shipments come clearly marked on the delivery note.
No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products.
Warranty coverage remains fully valid, aligned with our validated shipping method.
Please store the product as per the datasheet instructions upon receipt.
Find out more -
https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Conditional Ambient, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
TAF15 also known as TATA-binding protein-associated factor 15 is a RNA polymerase II-associated factor with approximate mass of 56 kDa. It belongs to the FET family of proteins which include FUS and EWS. This protein expresses widely in various tissues including the brain and immune cells. Mechanically TAF15 participates in transcription by mediating interactions between transcription factors and the RNA polymerase II complex.
Biological function summary
The protein helps regulate transcription initiation and elongation. TAF15 operates as a part of the transcription pre-initiation complex working closely with other transcription-associated factors to control gene expression. Its role extends beyond the nucleus as it may participate in RNA processing and transport due to its ability to bind RNA.
Pathways
TAF15 plays a role in the regulation of transcription from RNA polymerase II promoters. It interacts with numerous other proteins such as TFIID and RNA polymerase II subunits facilitating transcriptional regulation. TAF15 also associates with pathways related to stress response and cellular growth emphasizing its role in maintaining cellular integrity and function.
TAF15 links to certain forms of cancer and neurodegenerative diseases. Its misregulation or mutation associates with some sarcomas indicating a role in tumorigenesis possibly through interactions with oncogenic proteins like EWS. In neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) TAF15 might be implicated potentially through pathways shared with proteins like TDP-43 that are involved in RNA metabolism dysfunction.