Abcam, ab135996, Anti-C11orf17 antibody

Size: 100µg
Rabbit Polyclonal C11orf17 antibody. Suitable for WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human AKIP1.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human AKIP1. The exact immunogen used to generate this antibody is proprietary information.Q9NQ31

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C11orf17 also known as Chromosome 11 Open Reading Frame 17 is a protein with a molecular mass of approximately 52 kDa. This protein is expressed in various tissues but it shows higher expression levels in the brain and testis. The specific mechanistic role of C11orf17 is still under investigation but it has been linked to cellular regulation processes potentially through interactions with other proteins.
Biological function summary
C11orf17 seems to play a role in cellular differentiation and development. It is not known to be part of any multi-protein complexes definitively but it engages in interactions with various cellular components to influence cell cycle progression. Studies suggest it might have regulatory impacts on gene expression affecting transcriptional activities in the cells where it is expressed.
Pathways
C11orf17 is implicated in the Wnt signaling pathway a critical pathway for controlling cell fate decisions. Through this pathway it interacts with key proteins such as beta-catenin and possibly influences downstream signaling events responsible for cell proliferation. Additionally it relates to the MAPK pathway another signal transduction pathway that affects cellular responses to growth signals.
C11orf17 has been associated with cancer particularly in terms of its expression levels correlating with tumor progression. Changes in C11orf17 expression might influence cancer pathways through its interaction with beta-catenin. This protein is also related to neurodevelopmental disorders possibly impacting neurological pathways via its expression in the brain and connection to proteins involved in cognitive processes.