Abcam, ab141109, Dexrazoxane hydrochloride, Topoisomerase II inhibitor

Size: 10mg / 50mg
MW 268.27 Da, Purity >98%. Topoisomerase II inhibitor. Intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters. Reduces ROS° production and activates the PI3K/Akt survival pathway. Cardioprotective effects when co-administered with doxorubicin (ab142006) in vivo .
Key facts
CAS number:24584-09-6,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:268.27 Da,
Molecular formula:C11H16N4O4,
PubChem:71384,
Nature:Synthetic,
Solubility:0.1 M Borate Buffer (pH 9) 8.7 - 13 (mg/mL)Soluble in water to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:Dexrazoxane,
Biological description:Topoisomerase II inhibitor. Intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters. Reduces ROS° production and activates the PI3K/Akt survival pathway. Cardioprotective effects when co-administered with doxorubicin (ab142006) in vivo.,
Canonical smiles:CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2,
Isomeric smiles:C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2,
InChi:InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1,
InChiKey:BMKDZUISNHGIBY-ZETCQYMHSA-N,
IUPAC Name:4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months