Abcam, ab141231, CK 666, Actin polymerization inhibitor

Size: 10mg / 50mg
MW 296.3 Da, Purity >99%. Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC 50 = 17 μM), SpArp2/3 (IC 50 = 5 μM) and HsArp2/3 complexes (IC 50 = 4 μM) by preventing a shift into an active conformation.
Key facts
CAS number:442633-00-3,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:296.3 Da,
Molecular formula:C18H17FN2O,
PubChem:589075,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 100 mM,
Biochemical name:2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide,
Biological description:Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC50 = 17 μM), SpArp2/3 (IC50 = 5 μM) and HsArp2/3 complexes (IC50= 4 μM) by preventing a shift into an active conformation.,
Canonical smiles:CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CC=C3F,
InChi:InChI=1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22),
InChiKey:UXRKUKRXVWJFER-UHFFFAOYSA-N,
IUPAC Name:2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months