Abcam, ab141411, Lactacystin, proteasome inhibitor

Size: 200µg
MW 376.4 Da, Purity >95%. Potent, irreversible, cell-permeable, selective 20S proteasome inhibitor (IC 50 = 70 nM). Inhibits cell-cycle progression and induces neurite outgrowth in vitro . Anti-bacterial and antitumor agent. Active in vivo and in vitro .
Key facts
CAS number:133343-34-7,
Purity:>95%,
Molecular weight:376.4 Da,
Molecular formula:C15H24N2O7S,
PubChem:3870,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:2-(Acetylamino)-3-[({3-hydroxy-2-[1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)sulfanyl]propanoic acid,
Biological description:Potent, irreversible, cell-permeable, selective 20S proteasome inhibitor (IC50 = 70 nM). Inhibits cell-cycle progression and induces neurite outgrowth in vitro. Anti-bacterial and antitumor agent. Active in vivo and in vitro.,
Canonical smiles:CC1C(C(NC1=O)(C(C(C)C)O)C(=O)SCC(C(=O)O)NC(=O)C)O,
InChi:InChI=1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23),
InChiKey:DAQAKHDKYAWHCG-UHFFFAOYSA-N,
IUPAC Name:2-acetamido-3-[3-hydroxy-2-(1-hydroxy-2-methylpropyl)-4-methyl-5-oxopyrrolidine-2-carbonyl]sulfanylpropanoic acid

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1709 Lactacystin (Synthetic). 1709-200 is the same size as the 200 μg size of ab141411.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months