Abcam, ab141412, clasto-Lactacystin beta-lactone, 20S proteasome inhibitor

Size: 100µg
MW 213.23 Da, Purity >95%. Potent, irreversible and cell-permeable 20S proteasome inhibitor (IC 50 = 50 nM). Active metabolite of lactacystin (ab141411). Inhibits cell-cycle progression in cancer cells. Antitumor agent. Active in vivo and in vitro .
Key facts
CAS number:154226-60-5,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:213.23 Da,
Molecular formula:C10H15NO4,
PubChem:9794358,
Nature:Synthetic,
Solubility:Soluble in DMSO to 75 mMSoluble in water to 10 mM,
Biochemical name:Clasto-lactacystin beta-lactone,
Biological description:Potent, irreversible and cell-permeable 20S proteasome inhibitor (IC50 = 50 nM). Active metabolite of lactacystin (ab141411). Inhibits cell-cycle progression in cancer cells. Antitumor agent. Active in vivo and in vitro.,
Canonical smiles:CC1C2C(C(=O)O2)(NC1=O)C(C(C)C)O,
Isomeric smiles:C[C@@H]1[C@H]2[C@](C(=O)O2)(NC1=O)[C@H](C(C)C)O,
InChi:InChI=1S/C10H15NO4/c1-4(2)6(12)10-7(15-9(10)14)5(3)8(13)11-10/h4-7,12H,1-3H3,(H,11,13)/t5-,6+,7+,10-/m1/s1,
InChiKey:FWPWHHUJACGNMZ-NBBQQVJHSA-N,
IUPAC Name:(1R,4R,5S)-1-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1710 Clasto-Lactacystin ß-lactone. 1710-100 is the same size as the 100 μg size of ab141412.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months