Abcam, ab141431, Gemcitabine hydrochloride, Deoxycytidine analog

Size: 25mg / 100mg
MW 299.66 Da, Purity >99%. Potent specific, deoxycytidine analog. Pro-drug phosphorylated by deoxycytidine kinase to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). Cell cycle specific, inhibits the S and G 1 phase. Antitumor activity in vitro and in vivo .
Key facts
CAS number:122111-03-9,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:299.66 Da,
Molecular formula:C9H12ClF2N3O4,
PubChem:60749,
Nature:Synthetic,
Solubility:Soluble in water to 100 mMSoluble in DMSO to 50 mM,
Biochemical name:Gemcitabine hydrochloride,
Biological description:Potent specific, deoxycytidine analog. Pro-drug phosphorylated by deoxycytidine kinase to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). Cell cycle specific, inhibits the S and G1 phase. Antitumor activity in vitro and in vivo.,
Canonical smiles:C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl,
Isomeric smiles:C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.Cl,
InChi:InChI=1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1,
InChiKey:OKKDEIYWILRZIA-OSZBKLCCSA-N,
IUPAC Name:4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions