Abcam, ab141487, LDN-57444, UCH-L1 inhibitor

Size: 5mg / 25mg
MW 397.6 Da, Purity >98%. Reversible, competitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor (K i = 0.4 μM. Increases ubiquitinated protein levels and decreases proteasome activity. Also induces apoptosis.
Key facts
CAS number:668467-91-2,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:397.6 Da,
Molecular formula:C17H11Cl3N2O3,
PubChem:16760696,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:(Z)-3-(acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)indolin-2-one,
Biological description:Reversible, competitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor (Ki = 0.4 μM. Increases ubiquitinated protein levels and decreases proteasome activity. Also induces apoptosis.,
Canonical smiles:CC(=O)ON=C1C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl,
Isomeric smiles:CC(=O)O/N=C\1/C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl,
InChi:InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-,
InChiKey:OPQRFPHLZZPCCH-PGMHBOJBSA-N,
IUPAC Name:[(Z)-[5-chloro-1-[(2,5-dichlorophenyl)methyl]-2-oxoindol-3-ylidene]amino] acetate

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2016 LDN-57444. 2016-25 is the same size as the 25 mg size of ab141487.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months