Abcam, ab141491, Ro 3306, cyclin-dependent kinase (Cdk1) inhibitor

Size: 1mg / 5mg
MW 351.4 Da, Purity >99%. Selective cyclin-dependent kinase (Cdk1) inhibitor (K i values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A, respectively). Enhances downstream p53 signaling. Induces G2/M-phase cell cycle arrest and apoptosis.
Key facts
CAS number:872573-93-8,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:351.4 Da,
Molecular formula:C18H13N3OS2,
PubChem:11631681,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:CID 11631681,
Biological description:Selective cyclin-dependent kinase (Cdk1) inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A, respectively). Enhances downstream p53 signaling. Induces G2/M-phase cell cycle arrest and apoptosis.,
Canonical smiles:C1=CC2=C(C=CC(=C2)C=C3C(=O)N=C(S3)NCC4=CC=CS4)N=C1,
Isomeric smiles:C1=CC2=C(C=CC(=C2)/C=C\3/C(=O)N=C(S3)NCC4=CC=CS4)N=C1,
InChi:InChI=1S/C18H13N3OS2/c22-17-16(24-18(21-17)20-11-14-4-2-8-23-14)10-12-5-6-15-13(9-12)3-1-7-19-15/h1-10H,11H2,(H,20,21,22)/b16-10-,
InChiKey:XOLMRFUGOINFDQ-YBEGLDIGSA-N,
IUPAC Name:(5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months