Abcam, ab141847, Roscovitine, CDK inhibitor

Size: 2mg / 10mg
MW 354.4 Da, Purity >99%. Cell-permeable, selective inhibitor of cyclin-dependent kinases (CDKs), displaying higher potency and selectivity compared to olomoucine (ab120938). p34cdc2 inhibitor (IC 50 = 0.2 μM). Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic.
Key facts
CAS number:186692-46-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:354.4 Da,
Molecular formula:C19H26N6O,
PubChem:160355,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mMSoluble in ethanol to 25 mM,
Biochemical name:Seliciclib,
Biological description:Cell-permeable, selective inhibitor of cyclin-dependent kinases (CDKs), displaying higher potency and selectivity compared to olomoucine (ab120938). p34cdc2 inhibitor (IC50 = 0.2 μM). Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic.,
Canonical smiles:CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3,
Isomeric smiles:CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3,
InChi:InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1,
InChiKey:BTIHMVBBUGXLCJ-OAHLLOKOSA-N,
IUPAC Name:(2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions