Abcam, ab142074, PAC-1, caspase-3 activator

Size: 10mg
MW 392.5 Da, Purity >95%. Potent caspase-3 activator (IC 50 = 220 nM). Also activates caspase-7 (IC 50 = 4.5 μM). Proapoptotic in vitro . Anticancer activity in vivo . Orally active.
Key facts
CAS number:315183-21-2,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:392.5 Da,
Molecular formula:C23H28N4O2,
PubChem:6851947,
Nature:Synthetic,
Solubility:Soluble in water to 5 mMSoluble in DMSO to 25 mM,
Biochemical name:CID 6851947,
Biological description:Potent caspase-3 activator (IC50 = 220 nM). Also activates caspase-7 (IC50 = 4.5 μM). Proapoptotic in vitro. Anticancer activity in vivo. Orally active.,
Canonical smiles:C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O,
Isomeric smiles:C=CCC1=CC=C/C(=C/NNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)/C1=O,
InChi:InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,24H,1,7,12-15,17-18H2,(H,25,28)/b21-16-,
InChiKey:XSGXRYNZNGUGEJ-PGMHBOJBSA-N,
IUPAC Name:2-(4-benzylpiperazin-1-yl)-N'-[(Z)-(6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1654 PAC-1. 1654-10 is the same size as the 10 mg size of ab142074.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months