Abcam, ab142080, Tetrahydrouridine, cytidine deaminase inhibitor

Size: 10mg / 25mg
Tetrahydrouridine (ab142080) is a potent competitive cytidine deaminase (CDA) inhibitor (IC 50 = 152 µM) that modulates antiproliferative effects. The molecular weight of Tetrahydrouridine (THU) is 248.23 g/mol. - Orally active - Available in different sizes to fit your experiment needs
Key facts
CAS number:18771-50-1,
Purity:>80%,
Molecular weight:248.23 Da,
Molecular formula:C9H16N2O6,
PubChem:270480,
Nature:Synthetic,
Solubility:Soluble in water to 100 mM,
Biochemical name:2(1H)-pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl-,
Biological description:Competitive cytidine deaminase inhibitor (IC50= 152 μM). Modulates antiproliferative effects. Orally active.,
Canonical smiles:C1CN(C(=O)NC1O)C2C(C(C(O2)CO)O)O,
InChi:InChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16),
InChiKey:UCKYOOZPSJFJIZ-UHFFFAOYSA-N,
IUPAC Name:1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one

Product details:
Tetrahydrouridine (THU) is a synthetic pyrimidine nucleoside analogue and is a well characterized and potent inhibitor of cytidine deaminase (CDA). Cytidine deaminase is a key enzyme involved in the pyrimidine salvage pathway.
Use our Tetrahydrouridine, cytidine deaminase inhibitor (ab142080) for applications related to nucleotide metabolism and cancer-programmed cell death.
This product is manufactured by BioVision, an Abcam company and was previously called 1671 Tetrahydrouridine. 1671-25 is the same size as the 25 mg size of ab142080.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months