Abcam, ab142195, NSC-687852, USP14 and UCHL5 inhibitor

Size: 5mg
MW 419.4 Da, Purity >98%. Cell-permeable USP14 and UCHL5 inhibitor. Apoptotic agent. Induces mitochondrial apoptosis via cathepsin D-dependent caspase-cleavage. Shows antitumor effects in vivo. .
Key facts
CAS number:1009817-63-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:419.4 Da,
Molecular formula:C22H17N3O6,
PubChem:5351435,
Nature:Synthetic,
Solubility:Soluble in DMSO to 75 mM,
Biochemical name:(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one,
Biological description:Cell-permeable USP14 and UCHL5 inhibitor. Apoptotic agent. Induces mitochondrial apoptosis via cathepsin D-dependent caspase-cleavage. Shows antitumor effects in vivo.,
Canonical smiles:C=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1,
Isomeric smiles:C=CC(=O)N1C/C(=C\C2=CC=C(C=C2)[N+](=O)[O-])/C(=O)/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/C1,
InChi:InChI=1S/C22H17N3O6/c1-2-21(26)23-13-17(11-15-3-7-19(8-4-15)24(28)29)22(27)18(14-23)12-16-5-9-20(10-6-16)25(30)31/h2-12H,1,13-14H2/b17-11+,18-12+,
InChiKey:GFARQYQBWJLZMW-JYFOCSDGSA-N,
IUPAC Name:(3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2021 NSC-687852. 2021-25 is the same size as the 25 mg size of ab142195.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months