Abcam, ab142209, SKI-I, Sphingosine Kinase Inhibitor

Size: 5mg / 25mg
MW 410.5 Da, Purity >90%. Specific non-lipid sphingosine kinase (SK) inhibitor. Inhibits SK1 and SK2. Inhibits sphingosine 1-phosphate (S1P) production and pro-apoptotic. Induces autophagy. Cell permeable and active in vivo and in vitro .
Key facts
CAS number:306301-68-8,
Purity:>90%,
Form:SolidSee storage information,
Molecular weight:410.5 Da,
Molecular formula:C25H22N4O2,
PubChem:137269090,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:SKI-I, Sphingosine Kinase Inhibitor,
Biological description:Specific non-lipid sphingosine kinase (SK) inhibitor. Inhibits SK1 and SK2. Inhibits sphingosine 1-phosphate (S1P) production and pro-apoptotic. Induces autophagy. Cell permeable and active in vivo and in vitro.,
Canonical smiles:C1C(NNC1C(=O)NN=CC2=C(C=CC3=CC=CC=C32)O)C4=CC5=CC=CC=C5C=C4,
Isomeric smiles:C1C(NNC1C(=O)N/N=C/C2=C(C=CC3=CC=CC=C32)O)C4=CC5=CC=CC=C5C=C4,
InChi:InChI=1S/C25H22N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-13,15,22-23,27-28,30H,14H2,(H,29,31)/b26-15+,
InChiKey:LMCALHGHWCFFHD-CVKSISIWSA-N,
IUPAC Name:N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-5-naphthalen-2-ylpyrazolidine-3-carboxamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months