Abcam, ab142216, C59, Wnt Antagonist, Wnt signaling pathway inhibitor

Size: 1mg / 5mg
MW 379.5 Da, Purity >97%. Potent Wnt signaling pathway inhibitor. Inhibits porcupine (PORCN) required for Wnt palmitoylation, secretion, and biological activity. Inhibits Wnt-mediated transcription (IC 50 = 74 pM) and cell proliferation. Active in vivo. .
Key facts
CAS number:1243243-89-1,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:379.5 Da,
Molecular formula:C25H21N3O,
PubChem:57519544,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide,
Biological description:Potent Wnt signaling pathway inhibitor. Inhibits porcupine (PORCN) required for Wnt palmitoylation, secretion, and biological activity. Inhibits Wnt-mediated transcription (IC50 = 74 pM) and cell proliferation. Active in vivo.,
Canonical smiles:CC1=NC=CC(=C1)C2=CC=C(C=C2)CC(=O)NC3=CC=C(C=C3)C4=CN=CC=C4,
InChi:InChI=1S/C25H21N3O/c1-18-15-22(12-14-27-18)20-6-4-19(5-7-20)16-25(29)28-24-10-8-21(9-11-24)23-3-2-13-26-17-23/h2-15,17H,16H2,1H3,(H,28,29),
InChiKey:KHZOJCQBHJUJFY-UHFFFAOYSA-N,
IUPAC Name:2-[4-(2-methylpyridin-4-yl)phenyl]-N-(4-pyridin-3-ylphenyl)acetamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months