Abcam, ab142274, Dantrolene sodium, ryanodine receptor antagonist

Size: 100mg / 250mg
MW 336.23 Da, Purity >98%. Ryanodine receptor antagonist. Calcium channel inhibitor. Reduces calcium flux across the sarcoplasmic reticulum. Displays selectivity for RYR1 and RYR3 over RYR2. Crosses the blood-brain barrier and active in vivo. .
Key facts
CAS number:14663-23-1,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:336.23 Da,
Molecular formula:C14H9N4NaO5,
PubChem:6604100,
Nature:Synthetic,
Solubility:Soluble in water to 5 mM with warmingSoluble in DMSO to 10 mM,
Biochemical name:Dantrolene sodium,
Biological description:Ryanodine receptor antagonist. Calcium channel inhibitor. Reduces calcium flux across the sarcoplasmic reticulum. Displays selectivity for RYR1 and RYR3 over RYR2. Crosses the blood-brain barrier and active in vivo.,
Canonical smiles:C1C(=NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+],
Isomeric smiles:C1C(=NC(=O)N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+],
InChi:InChI=1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);/q;+1/p-1/b15-7+;,
InChiKey:KSRLIXGNPXAZHD-HAZZGOGXSA-M,
IUPAC Name:sodium;3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months