Abcam, ab142685, Aeroplysinin (Aeroplysinin-1), antiangiogenic agent

Size: 100µg / 1mg
MW 338.98 Da, Purity >95%. Potent antiangiogenic agent. Inhibits COX-2 expression. Selectivity for endothelial cells. Able to induce apoptosis via capsase activation, chromatin condensation and nuclear fragmentation. Antibiotic and cytotoxic effects (IC 50 = 3 μm) and displays a wide-spectrum antitumor activity. Active in vivo. .
Key facts
CAS number:28656-91-9,
Purity:>95%,
Source:Aplysina aerophoba,
Molecular weight:338.98 Da,
Molecular formula:C9H9Br2NO3,
PubChem:100308,
Nature:Native,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 25 mM,
Biochemical name:Aeroplysinin I,
Biological description:Potent antiangiogenic agent. Inhibits COX-2 expression. Selectivity for endothelial cells. Able to induce apoptosis via capsase activation, chromatin condensation and nuclear fragmentation. Antibiotic and cytotoxic effects (IC50 = 3 μm) and displays a wide-spectrum antitumor activity. Active in vivo.,
Canonical smiles:COC1=C(C(C(C=C1Br)(CC#N)O)O)Br,
Isomeric smiles:COC1=C([C@@H]([C@@](C=C1Br)(CC#N)O)O)Br,
InChi:InChI=1S/C9H9Br2NO3/c1-15-7-5(10)4-9(14,2-3-12)8(13)6(7)11/h4,8,13-14H,2H2,1H3/t8-,9-/m0/s1,
InChiKey:BGYNLOSBKBOJJD-IUCAKERBSA-N,
IUPAC Name:2-[(1S,6R)-3,5-dibromo-1,6-dihydroxy-4-methoxycyclohexa-2,4-dien-1-yl]acetonitrile

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, The product can be stored for up to 12 months