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BRAND / VENDOR: Abcam

Abcam, ab142778, Indo-1 AM, fluorescent Ca2+ indicator

CATALOG NUMBER: ab142778
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Product Description

Size: 1mg
MW 1009.9 Da, Purity >95%. Cell-permeable, ratiometric, fluorescent Ca2+ indicator. Binds to Ca2+ with high affinity (Kd = 230 nM). Fluoresces blue/violet and fluorescence increases upon Ca2+ binding. Cell-impermeable form, Indo 1 K+ salt (ab142779) also available. Emission and excitation shifts from 475 to 401 nm and 346 to 330 nm respectively depending on Ca2+ binding.
Key facts
CAS number:112926-02-0,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:1009.9 Da,
Molecular formula:C47H51N3O22,
PubChem:123918,
Nature:Synthetic,
Solubility:Soluble in DMSO,
Biochemical name:Indo-1 pentaacetoxymethyl ester,
Biological description:Cell-permeable, ratiometric, fluorescent Ca2+ indicator. Binds to Ca2+ with high affinity (Kd = 230 nM). Fluoresces blue/violet and fluorescence increases upon Ca2+ binding. Cell-impermeable form, Indo 1 K+ salt (ab142779) also available. Emission and excitation shifts from 475 to 401 nm and 346 to 330 nm respectively depending on Ca2+ binding.,
Canonical smiles:CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=CC4=C(N3)C=C(C=C4)C(=O)OCOC(=O)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C,
InChi:InChI=1S/C47H51N3O22/c1-28-7-11-39(49(19-43(56)68-23-63-29(2)51)20-44(57)69-24-64-30(3)52)41(15-28)61-13-14-62-42-18-35(37-16-34-8-9-36(17-38(34)48-37)47(60)72-27-67-33(6)55)10-12-40(42)50(21-45(58)70-25-65-31(4)53)22-46(59)71-26-66-32(5)54/h7-12,15-18,48H,13-14,19-27H2,1-6H3,
InChiKey:CAWBRCOBJNWRLK-UHFFFAOYSA-N,
IUPAC Name:acetyloxymethyl 2-[4-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-3-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months


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