Abcam, ab143145, Rotenone, mitochondrial electron transport chain inhibitor

Size: 1g / 5g
MW 394.4 Da, Purity >97%. Mitochondrial electron transport chain complex I inhibitor (IC 50 values are 1.7 - 2.2 μM). Potent NADH oxidation inhibitor (IC 50 = 3.4 nM). Suppresses microtubule assembly. Induces BRL cell apoptosis. Shows antiproliferative effects. Shows central effects. Induces parkinsonian behavior in vivo. .
Key facts
CAS number:83-79-4,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:394.4 Da,
Molecular formula:C23H22O6,
PubChem:6758,
Nature:Synthetic,
Solubility:Soluble in ethanol to 5 mMSoluble in DMSO to 100 mM,
Biochemical name:Rotenone,
Biological description:Mitochondrial electron transport chain complex I inhibitor (IC50 values are 1.7 - 2.2 μM). Potent NADH oxidation inhibitor (IC50 = 3.4 nM). Suppresses microtubule assembly. Induces BRL cell apoptosis. Shows antiproliferative effects. Shows central effects. Induces parkinsonian behavior in vivo.,
Canonical smiles:CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC,
Isomeric smiles:CC(=C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC,
InChi:InChI=1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1,
InChiKey:JUVIOZPCNVVQFO-HBGVWJBISA-N,
IUPAC Name:(1S,6R,13S)-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months